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Some evidence that suggests Epitalon’s potential effects on the effective and accelerated wound healing process.


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What is Epitalon?

Epitalon, also commonly known as Epithalon peptide or Epithalone is a synthetic tetrapeptide with four amino acids in its structure. The amino acid sequence of Epitalon is Ala-Glu-Asp-Gly with a molecular formula C14H22N4O9 (1).

Epitalon is a derivative of Epithalamin or Epithalamine which is a polypeptide naturally released from the pineal gland. For those of you who haven’t heard about the pineal gland, it is a small pea-shaped gland located deep in the brain. It is also referred to as the “third eye”

This synthetic peptide was originally discovered by Russian scientist Vladimir Khavinson. Since then most of the clinical studies centered around Epitalon were carried out in St. Petersburg Institute of Bioregulation and Gerontology.

Because of the potential benefits of peptide Epitalon, it has been included in the modern age peptide therapy.

How Does Epitalon Work?

DNA, also known as deoxyribonucleic acid is a double-stranded molecule, and one of the critical components of our genetic makeup. It lies in the nucleus of the cell and replicates itself whenever the cell undergoes cell division.

DNA molecules are made up of multiple chromosomes which carry invaluable information in our body. The tips of DNA strands are covered with Telomeres, a repetitive sequence of nucleotide bases whose critical function is to protect the DNA, and prevent any loss of genetic information while a cell undergoes cell division.

A natural enzyme called telomerase helps cells reproduce telomeres. Significantly increased telomere lengths as a result of telomerase activity ensure better cell health, and keep the genetic information intact.

Now one can understand why the aging process is triggered. This is because the telomerase production significantly falls with time. Thus, one experiences the aging process and other age-related diseases. I am sure by this time you must have started to get an idea about how Epitalon would help you!

Epitalon is a synthetic telomerase activator enzyme that upregulates the synthesis of telomerase enzyme by the pineal gland. Thus, telomeres at the end of chromosomes are renewed and more telomeres are available at the tips of DNA strands even after a cell divides repeatedly.

Besides, Epitalon treatment also stimulates melatonin production as well as regulates its secretion. This helps in the restoration of normal circadian rhythm as melatonin secretion is a critical chemical that balances the sleep/wake cycle.

Some human clinical studies also suggest that this synthetic pineal peptide Epitalon also modulates the blood levels of gonadotropins.

Benefits of Epitalon

Considering the mechanism of action of Epitalon, one of the exclusive use of Epitalon is to ensure better cell health by lengthening the telomeres. This eventually ensues in delaying the onset of the aging process, and also increases the life expectancy of an individual.

In one of the clinical trials, aging rats demonstrated extension in their aging process. This significantly confirms the findings of human clinical trials.

Human clinical studies conducted in the past also show that Epitalon treatment significantly reduced the risk of developing age-related neurodegenerative diseases, such as Alzheimer’s, dementia, heart disease, etc.

Perhaps Epitalon’s antioxidant effects have been a strong area of research in modern clinical trials, and results suggest that Epitalon destroys free radicals and inhibits lipid oxidation, thus protecting against oxidative stress. Epitalon produces antioxidant effects in the body by activating antioxidant enzymes, such as glutathione peroxidase.

This can indirectly also suppress cancer growth by destroying cancer cells in you and potentially curing you. This may also mitigate any risks of developing spontaneous tumors as well.

Research suggests that Epitalon regulates the functioning of T cells (one of the types of white blood cells) by stimulating the production of interferon-gamma.

Because Epitalon regulates melatonin production, you will definitely experience an improvement in your circadian rhythm, thus you will sleep deeper and better.

Peptide Epitalon also ensures the rejuvenation of aging skin fibroblasts by inhibiting the synthesis of MMP9 protein. This may result in better and smooth skin as well as an overall improved texture.

Although unclear, there is some evidence that suggests Epitalon’s potential effects on the effective and accelerated wound healing process.

Some shocking threads also suggest that Epitalon may possess massive curing capabilities against Retinitis Pigmentosa, a rare genetic disorder.

Last but not least, people using Epitalon experienced mild resistance against emotional stress as well. Importantly, their coping mechanism significantly improved.

Epitalon Dosage

A human clinical trial conducted suggests that subjects experienced significant changes as compared to the control group when the optimal dosage range of Epitalon was 5 to 10mg per day. What I would suggest is that you start low at first, and then increase your dosage as your body gets accustomed to it!

If you are choosing a low dose initially, you can administer it all at once. However, if you are opting for a higher dose, I would suggest splitting it into 2 equal dosages and administering it one in the morning and the other at night.

Epitalon Cycle

This is a very critical question. Multiple studies suggest that the Epitalon cycle should only last somewhere between 2 to 3 weeks.

The maximal Epitalon cycle that you should repeat is two times per year. A break of 4 to 6 months is essentially required before you can start on your Epitalon cycle again.

Epitalon Stack

While not many studies are available that suggest potential peptides that can be stacked with Epitalon, one of the research chemicals Thymalin may do the job well. Thymalin is exclusively related to managing your immune and endocrine systems. Thymalin enhances your immune functioning by stimulating the maturation of t cells by the Thymus. Besides, it upregulates the synthesis of many other peptide hormones.

Stacking Epitalon with Thymalin will not only strengthen your immune system synergistically but also cast strong anti-aging and antioxidant effects. In one of the studies subjects that were exposed to both the peptide stacked experienced a longer life span as compared to the control group.

While more studies need to be performed, the combo seems to work pretty fine synergistically at the moment!

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